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MRI right before or after surgery does not benefit women with early breast...

Memorial Sloan-Kettering Cancer Center study shows that the use of MRI before or immediately after surgery in women with DCIS was not associated with reduced local recurrence or contralateral breast...

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Researchers uncover genetic cause of childhood leukemia

For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's...

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Oncogenic signatures mapped in TCGA a guide for the development of...

Clinical trial design for new cancer therapies has historically been focused on the tissue of origin of a tumor, but a paper from researchers at Memorial Sloan-Kettering Cancer Center published on...

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Newly engineered monoclonal antibody moves toward clinical testing

(Medical Xpress)—Using monoclonal antibodies to fight cancer is a complex, yet promising area of study. At Memorial Sloan Kettering Cancer Center, physician-scientists have focused their attention on...

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Research links obesity to poor survival in tongue cancer patients

(Medical Xpress)—Cancer experts from Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College are working side by side to unravel the mysterious link between obesity and cancer. Most...

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Cell therapy shows remarkable ability to eradicate cancer in clinical study

Investigators from Memorial Sloan Kettering Cancer Center have reported more encouraging news about one of the most exciting methods of cancer treatment today. The largest clinical study ever conducted...

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Study reveals mechanisms cancer cells use to establish metastatic brain tumors

New research from Memorial Sloan Kettering provides fresh insight into the biologic mechanisms that individual cancer cells use to metastasize to the brain. Published in the February 27 issue of Cell,...

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Phase I data suggest PLX3397 is a potential therapy for patients with...

A novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis (PVNS), a rare neoplastic joint disorder, according to new phase I data from Memorial Sloan...

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Genomic tumor testing to match lung cancer patients with targeted drugs...

New data from a study led by Memorial Sloan Kettering physicians that used targeted therapy for patients with the most common type of lung cancer has helped transform treatment for the disease.

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Transplantation shown to be highly effective in treating immune deficiency in...

Babies who are born with severe combined immunodeficiency (SCID) can be successfully treated with a transplant of blood-forming stem cells, according to experts led by Memorial Sloan Kettering's...

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The newest precision medicine tool: Prostate cancer organoids

Research led by investigators at Memorial Sloan Kettering Cancer Center has shown for the first time that organoids derived from human prostate cancer tumors can be grown in the laboratory, giving...

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Researchers find novel way body defends against harmful bacteria

Bacterial infections can cause major problems for people undergoing treatment for cancer and other diseases. The concern is especially acute during hospitalization, when patients often have weakened...

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Positive study data could improve standard of care for Hodgkin lymphoma patients

In a late-stage clinical trial, Hodgkin lymphoma (HL) patients who received brentuximab vedotin (BV) post-transplant lived longer without disease progression than patients who received only supportive...

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Studies show immunotherapy drugs improve outcomes in Hodgkin lymphoma patients

In recent years, a number of scientific breakthroughs have led to the development of drugs that unleash the power of the immune system to recognize and attack cancer. Studies presented today at the...

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Study shows new kind of targeted drug has promise for leukemia patients

A new type of cancer therapy that targets an oncometabolite produced dramatic results in patients with advanced leukemia in an early-phase clinical trial. The study, led by Eytan M. Stein, MD, a...

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Testing for mutations identified in squamous cell lung cancer tumors helps...

Screening lung cancer tumor samples for cancer-causing, or "driver," genetic mutations can help physicians tailor patients' treatments to target those specific mutations. While scientists have...

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Adoptive cell transfer: New technique could make cell-based immune therapies...

A team led by Michel Sadelain, MD, PhD, Director of the Center for Cell Engineering at Memorial Sloan-Kettering Cancer Center, has shown for the first time the effectiveness of a new technique that...

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Drug shown to reverse radioiodine resistance in some advanced thyroid cancers

The experimental drug selumetinib may allow some patients with advanced thyroid cancer to overcome resistance to radioiodine (RAI), the most effective therapy for the disease, according to new research...

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New monoclonal antibody developed that can target proteins inside cancer cells

Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are...

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New drug improves progression-free survival, shrinks tumors in rare cancer...

The experimental drug selumetinib is the first targeted therapy to demonstrate significant clinical benefit for patients with metastatic uveal melanoma, according to new Memorial Sloan-Kettering Cancer...

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Combination of drugs produces dramatic tumor responses in advanced melanoma...

The combination of the immunotherapy drug ipilimumab and the investigational antibody drug nivolumab led to long-lasting tumor shrinkage in more than half of patients with metastatic melanoma,...

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Researchers develop new method for tracking cell signaling

Researchers at Memorial Sloan-Kettering Cancer Center, together with collaborators in Germany, have developed a new method for identifying the cell of origin of intracellular and secreted proteins...

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Most popular ovarian cancer cell lines do not resemble ovarian cancer

(Medical Xpress)—Researchers from Memorial Sloan-Kettering Cancer Center recently discovered that the most frequently used cancer cell lines in ovarian cancer research are not suitable models of...

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Study suggests pattern in lung cancer pathology may predict cancer recurrence...

A new study by thoracic surgeons and pathologists at Memorial Sloan-Kettering Cancer Center shows that a specific pattern found in the tumor pathology of some lung cancer patients is a strong predictor...

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Cancer researchers publish landmark "basket study"

Researchers from Memorial Sloan Kettering Cancer Center (MSK) have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on...

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Immunotherapy combination Nivolumab plus Ipilimumab receives FDA approval for...

Today, the US Food and Drug Administration (FDA) approved the immunotherapy combination nivolumab (Opdivo) plus ipilimumab (Yervoy) for use in patients with metastatic melanoma. This is the first-ever...

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How metastatic cancer cells evade detection by the immune system

Even after successful treatment, cancer can sometimes come back years later and spread to different organs. This is called latent metastasis. A new study by MSK scientists sheds light on how cancer...

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Despite pressing need, survey finds most americans unlikely to enroll in...

The lack of participation in clinical research may be the Achilles' heel of today's cancer community. According to a new survey of more than 1,500 consumers and nearly 600 physicians conducted on...

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FDA approves 'game changer' immunotherapy drug for bladder cancer

A new immunotherapy drug, atezolizumab, has been approved for patients with metastatic urothelial carcinoma, a type of bladder cancer. The drug represents the first new treatment for this form of the...

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